Ribosome Research Centre Pvt. Ltd.Ribosome Research Centre Pvt. Ltd.Ribosome Research Centre Pvt. Ltd.Ribosome Research Centre Pvt. Ltd.

In - Vivo Toxicology

OUR PRE CLINICAL SERVICES

In - Vivo Toxicology

Ribosome Research Centre provides comprehensive in-vivo toxicology and safety evaluation studies in rodents and non-rodents in compliance with OECD GLP and global regulatory guidelines.

In - Vivo Toxicology Services Scope

1

Mammalian Toxicology:

  • Acute Oral Toxicity
  • Acute Dermal Irritation / Toxicity
  • Acute Inhalation Toxicity
  • Skin Sensitization (GPMT/Buehler)
  • Maximum Tolerated Dose (MTD)
  • Dose Range Finding (DRF)
  • Repeated Dose Toxicity (28, 90 And 180 Days)
  • Developmental And Reproductive Toxicology
  • Carcinogenicity
  • Neurotoxicity
  • Bioassay
  • Abnormal Toxicity
2

Biocompatibility Testing for Medical Device As Per ISO 10993:

  • Intracutaneous Reactivity / Skin Irritation
  • Acute Systemic Toxicity
  • Material Mediated Pyrogenicity
  • Mucosal Irritation Test (Oral Mucosa, Penile, Vaginal, Rectal And Ocular Irritation)
  • Implantation (Local Tissue Effects After Implantation)
  • Sub-Acute Toxicity
  • Sub-Chronic Toxicity
  • Chronic Toxicity
  • Preparation Of Biological Evaluation Plan And Biological Evaluation Report
  • Toxicological Risk Assessment
3

Safety Pharmacology

  • Cardiometabolic
  • Antiplatelet Effect
  • Neuromuscular Pain
  • Sarcopenia
  • Anti-Osteoarthritic
  • Glaucoma
  • Migraine
  • Chronic Kidney Disease
  • High Fat Diet
  • Customised Based Studies As Per Requirement

Our Process

Our Approach To Accurate & Compliant Testing

Build your career in a research environment that values scientific curiosity, quality and teamwork. At Ribosome Research Centre, people contribute to work that supports the understanding of products and the evidence behind development decisions.

  • Requirement Understanding

    We begin by understanding your product, testing requirements, and regulatory objectives to define a clear analytical strategy.

  • Method Development & Planning

    Our team develops and optimizes analytical methods, ensuring alignment with ICH, USP, and global regulatory standards.

  • Testing & Analysis

    Samples are tested using advanced instrumentation such as LC-MS/MS, ICP-MS, and other validated techniques for accurate results.

  • Reporting & Compliance Support

    We deliver detailed, audit-ready reports and provide support for regulatory submissions and compliance requirements.

Call To Action

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